New Review - From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches
In this review, the authors provides an overview on the current state of drug…
What Happens to Our Brains When We Get Depressed?
The human brain, in all its complexity, is nearly impossible to model.…
Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data
A new methods paper out proposing a novel method for improving differential…
Large-scale transcriptomic studies provide insight into sex differences in depression
Dr. Marianne L. Seney, Dr. Jill Glausier, and Dr. Etienne Sibille published a…
Transcriptional Markers of Excitation-Inhibition Balance in Germ-Free Mice Show Region-Specific Dysregulation and Rescue After Bacterial Colonization
New paper out by Vivek Philip and colleagues, describing fascinating findings…
Behavioral deficits induced by somatostatin-positive GABA neuron silencing are rescued by alpha 5 GABA-A receptor potentiation
Corey Fee, former PhD student in the Sibille Lab, just published part of his…
The Guardian - New drug raises hopes of reversing memory loss in old age
Feb 2019. The Guardian publishes article on recent advances in the Sibille lab.…
New Research Article: Older molecular brain age in severe mental illness
Older molecular brain age in severe mental illnessMolecular Psychiatry, July…
New Research Paper in Neuroscience by Corey Fee
Chronic Stress-induced Behaviors Correlate with Exacerbated Acute…